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Active Ingredient: Ciprofloxacin

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Amount in a package: 60 PCS
Functionality: Antibiotics
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This information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. Proteomics verifies the presence of a protein and provides a direct measure of the quantity present.

An additional important reason that protein profiling is crucial is its power to analyze protein modifications.

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Phosphorylation is an example of posttranslational modification. Structural proteins can undergo phosphorylation during cell signaling and result in the protein becoming a target for binding to or interacting with a distinct group of proteins that recognize the phosphorylated domain.

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Ubiquitination is another post-translational type of modification. Ubiquitin is a small protein that can be affixed to certain protein substrates by means of enzymes known as E 3 ubiquitin ligases.

Identifying which proteins are polyubiquitinated can be helpful in understanding how protein pathways are regulated. In addition to phosphorylation and ubiquitination, proteins can undergo additional modifications via methylation, acetylation, glycosyl- Turk J Hematol.

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These modifications can be assessed only at the protein level and modifications of many proteins expressed by a cell can be determined at the same time using such proteomic methods as phosphoproteomics and glycoproteomics.

In addition to modifications, there is no doubt that protein localization and interactions are of vital importance to their function. Mislocalization of a protein or any problem in signal transduction can turn normal cells into abnormal cells, which is a well-known paradigm in carcinogenesis.

Protein profiling using proteomic methods can also be used to characterize these regulatory mechanisms.

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In summary, protein profiling provides a much better understanding of an organism, in terms of structure and function.

Use of protein profiling in the study of multiple proteins, protein forms, and protein families - almost always by comparing 2 different states diseased vs.

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  • Elucidation of protein-protein interactions and signaling pathways, identification of biomarkers useful for drug development, serum profiling to identify patient populations that respond to various treatments, and eventually medical diagnostics in the near future can be implemented for hematological malignancies via proteomics.

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